24+ Hyperpigmentation Nails Vitamin B12 Deficiency Symptoms Background. If you have anaemia caused by a vitamin b12 deficiency, you may have other symptoms, such as Vitamin b12 deficiency is rare in children, with nonspecific symptoms including failure to thrive, vomiting, anorexia, and neurologic changes a case of reversible generalized hyperpigmentation of the skin and nails with reversible premature gray hair due to vitamin b12 deficiency is reported.

Vitamin b12 deficiency anemia, of which pernicious anemia (pa) is a type, is a disease in which not enough red blood cells are produced due to a deficiency of vitamin b12.

Signs include hyperpigmentation on hands or toes (image: Vitamin b12 deficiency is rare in children, with nonspecific symptoms including failure to thrive, vomiting, anorexia, and neurologic changes a case of reversible generalized hyperpigmentation of the skin and nails with reversible premature gray hair due to vitamin b12 deficiency is reported. Vitamin b12, also called cobalamin, is a cofactor involved in essential body processes such as cellular metabolism, dna replication and red blood cell formation. Vitamin b12 deficiency refers to low levels of vitamin b12 in the body.